Skip to main content
BOPPP Trial
Supported by King's College NHS Foundation Trust

News

As of 12th May 2022, we have recruited 291 participants to BOPPP!

May – July 2022

  • Zoom refresher training drop in sessions for existing sites scheduled for:
    • Tuesday 24th May: 4 – 4:45pm
    • Thursday 27th May: 3 – 3:45pm
    • Tuesday 28th June: 4 – 4:45pm
    • Tuesday 12th July: 10:30 – 11:15am
  • Ix Meeting #2: Tuesday 14th June: 4 – 5pm
  • RN Meeting #2: Tuesday 5th July: 2 – 3pm
  • If you’d like to attend, please send an email to kch-tr.boppptrial@nhs.net and we will get back to you ASAP.

December 2021

  • 200th participant recruited to BOPPP

November 2021

  • Ix Meeting #1: Monday 8th November: 4 – 5pm

July 2021

  • Planned restart on Monday 5th July 2021

June 2021

  • Zoom refresher training drop in sessions for existing sites scheduled for:
    • Thursday 17th June: 2 – 2:45pm
    • Wednesday 23rd June: 2 – 2:45pm
    • Tuesday 29th June: 9 – 9:45am
    • Thursday 1st July: 2 – 2:45pm

December 2020

  • Trial paused due to COVID-19 as per recommendations
  • Existing sites encouraged to pre-screen for potential eligible patients

September 2020

  • Database change for protocol v1.5
  • Source document worksheets updated

August 2020

  • Newcastle re-opens to recruitment

July 2020

  • PRUH and St George’s re-open to recruitment

June 2020

  • KCH is first site to re-open recruitment following COVID-19 pause.
  • Guidance document v3.0 sent out to sites as to the procedure for restart

March 2020

  • Trial paused on 19th March 2020 due to COVID-19 pandemic
  • Guidance document v2.0 sent out for sites on how to manage their 6-monthly visits remotely

August 2019

  • BOPPP joins Twitter – catch us on @boppptrial 
  • Derby recruits their first patient!
  • Derby, Brighton, Frimley and the Royal Free become the 2nd, 3rd, 4th and 5th sites to be opened to recruit patients!
  • Nottingham and Devon & Exeter complete their Site Initiation Visit
  • Nottingham, Devon & Exeter confirm capability and capacity
  • BOPPP receives 
    • REC Favourable Opinion for clinical trial Protocol v1.4
    • HRA approval for clinical trial Protocol v1.4
    • Regulatory approval from the MHRA for clinical trial Protocol v1.4

July 2019

  • Royal Free confirm capability and capacity
  • St George’s, Frimley, Imperial and Royal Free complete their Site Initiation Visit 

June 2019

  • The first UK patient is recruited at King’s College Hospital – Denmark Hill
  • PRUH, Brighton, Plymouth and Derby complete their Site Initiation Visit 
  • King’s College Hospital – Denmark Hill is the first site to be opened to recruit patients! 
  • Frimley, Plymouth and Derby confirm capability and capacity

May 2019 

  • The first confirmation of site capability and capacity to deliver BOPPP is provided by King’s College Hospital NHS Foundation Trust that covers Denmark Hill and PRUH
  • St George’s confirm capability and capacity
  • The Trial Management Group host a Pan-London and Co-applicant Investigator meeting involving King’s College Hospital – Denmark Hill, King’s College Hospital – Princess Royal University Hospital (PRUH), St Georges, Imperial, Frimley, Royal Free and Barts

April 2019

  • BOPPP receives approval to start the trial from the Health Research Authority (HRA) for clinical trial Protocol v1.3

March 2019

  • BOPPP receives Research Ethics Committee (REC) Favourable Opinion for clinical trial Protocol v1.3
  • BOPPP receives regulatory approval from the Medicines & Healthcare products Regulatory Authority (MHRA) for clinical trial Protocol v1.3

January 2019

  • The BOPPP trial research grant starts with permission form the Department of Health and the NIHR

October 2018

  • King’s Health Partners make a press release promoting the BOPPP Trial

September 2018

  • British Liver Trust make a press release promoting the BOPPP Trial

July 2018